A new type of porous scaffold made of gelatin/nano hydroxyapatite
Publish date : 2013/08/30 Visited : 2510 News Topic : Nanomedicine News

A new type of porous scaffold made of gelatin/nano hydroxyapatite was designed and produced by Iranian researchers to recover bone tissue.

A new type of porous scaffold made of gelatin/nano hydroxyapatite was designed and produced by Iranian researchers to recover bone tissue.
The synthetic technique to produce the scaffold used in the research resulted in the obtaining of an appropriate porous structure to be used in bone tissue scaffold.

Dr. Mahmoud A’zami, Assistant Professor in tissue engineering from Faculty of Novel Medical Technologies of Tehran University of Medical Sciences, explained about the stages of the research, “In the first stage, an appropriate scaffold was designed and synthesized. In this part, a type of porous scaffold with a structure desirable to grow bone was produced by using solvent casting, freeze-drying, and layering. Then the synthesized scaffold was investigated by using non-biological tests and the common characterization methods. In order to study the biological properties of the synthesized scaffold, including its biocompatibility, and also to study its potential in growth and proliferation of bone cells, in vitro biological tests were carried out. In vivo tests were also carried out on the animal sample (rat) in calvaria zone in order to study the ability to recover the bone tissue where the scaffold has been placed.”

The synthetic technique to produce the scaffold used in the research resulted in the obtaining of an appropriate porous structure to be used in bone tissue scaffold. 

According to A’zami, further in vivo investigations were carried out to evaluate the product on larger animal samples such as rabbit, and it must be tested on even larger animals or humans in the future. In case the product is confirmed in future tests, the product presented in this research will be able to cure tiny bones damaged due to diseases or crash.

A sum total of three articles have so far been published and one invention has so far been filed in the country from the results of the research. One of the articles has been published in June 2012 in Journal of Biomaterials Science, Polymer Edition.

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